Why do i say that? Because there is a little glitch in the game which let you break all security stuffs with one picklock/multitool. These things are quite important in the game, so i suggest you to NOT spend skillpoints to the picklocking and Electronics skills. There are a lot of doors, gates, storages which requires more than one picklock or multitool.
There are 3 stages you can upgrade each skill and it requires a lot of skillpoints, BUT! - I can give you some advices which skills you should improve and which not. The game gives you skillpoints after every completed mission which you can spend for several skills, like hacking, weapon handling, swimming, picklocking, etc.